Imaging of small airways disease.

  title={Imaging of small airways disease.},
  author={Gerald F. Abbott and Melissa L. Rosado-de-Christenson and Santiago Enrique Rossi and Saul Suster},
  journal={Journal of thoracic imaging},
  volume={24 4},
Small airways disease includes a spectrum of inflammatory and fibrotic pulmonary diseases centered on the small conducting airways. High-resolution computed tomography plays a key role in the detection and classification of small airways disease and, when combined with relevant clinical and pathologic findings, leads to a more accurate diagnosis. The imaging manifestations of small airways disease on high-resolution computed tomography may be direct or indirect signs of small airway involvement… 

Imaging of Small Airways Diseases.

Bronchiolar Disorders Simplified

A simplified approach to the evaluation of bronchiolar disorders is provided by dividing them into 4 broad groups based on their predominant HRCT imaging features, which often are described in relation to the secondary pulmonary lobule.

Cystic and nodular lung disease.

Assessing and treating small airways disease in asthma and chronic obstructive pulmonary disease

Improving the efficiency of existing aerosolized therapy to direct drug to the appropriate lung regions may improve clinical efficacy and large studies are needed to determine whether better distal lung deposition leads to improvements in small airways function that are translated into clinically significant patient outcomes.

A Computer-based Analysis for Identification and Quantification of Small Airway Disease in Lung Computed Tomography Images: A Comprehensive Review for Radiologists.

This review aimed to describe the available methods for the identification and quantification of small airway disease on CT images and to discuss the challenges of implementing QCT metrics in clinical care for patients with small airways disease.

[Bronchiolitis. Part 1--anatomic features, classification, clinical presentation and imaging].

The present paper summarises the current knowledge, the classification, imaging, and the clinical presentation of bronchiolar disorders.

Diffuse Cystic Lung Disease of Unexplained Cause With Coexistent Small Airway Disease: A Possible Causal Relationship?

It is hypothesized that chronic damage to small airways may lead to cystic degeneration in a minority of patients, and precedents in relation to Sjogren syndrome and hypersensitivity pneumonitis raise the possibility of a causal association between pathologies in these 2 anatomic compartments.



Imaging of small airways disease.

High-resolution computed tomography scans can often accurately depict disease processes in the small airways and can occasionally lead to a specific diagnosis from among several clinically relevant possibilities.

Small airways diseases: detection and insights with computed tomography.

  • D. Hansell
  • Medicine
    The European respiratory journal
  • 2001
An understanding of the pathology and microscopic distribution of disease in relation to the airways allows some prediction of the likely computed tomography appearances in this wide spectrum of conditions, and thus helps to refine the differential diagnosis.

Imaging of small airways disease and chronic obstructive pulmonary disease.

  • D. Lynch
  • Medicine
    Clinics in chest medicine
  • 2008

Small airway diseases.

Radiologic and pathologic features of bronchiolitis.

The CT features presented in this article represent the typical features associated with each entity and can help to narrow the differential diagnosis of bronchiolitis.

Bronchiolar disorders: classification and diagnostic approach.

High-resolution computed tomographic scanning (HRCT) is currently the best imaging technique for the evaluation of patients suspected of having bronchiolitis, and the diagnostic approach to these diseases is discussed.

High-resolution CT of peripheral airways diseases.

Bronchiolar disorders.

The clinical relevance of a bronchiolar lesion is best determined by identifying the underlying histopathologic pattern and assessing the correlative clinico-physiologic-radiologic context.

Challenges in pulmonary fibrosis · 2 : Bronchiolocentric fibrosis

Bronchiolocentric fibrosis is essentially represented by the pathological pattern of constrictive fibrotic bronchiolitis obliterans, which is characterised by dyspnoea, airflow obstruction at lung function testing and air trapping with characteristic mosaic features on expiratory high resolution CT scans.

Pathology of Small Airways

The small conducting airways consist of the membranous bronchioles and the respiratory bronchiola and the histopathologic patterns associated with small airway injury are discussed.