Imaging of protein translocation in situ in skeletal muscle of living mice.


Skeletal muscle plays a key role in regulating whole body glucose homeostasis and severe dysfunction in insulin-mediated glucose uptake is the hallmark of insulin-resistant states and type II diabetes. Therefore it is highly pathophysiologically relevant to perform detailed studies of insulin signaling inside skeletal muscle cells in order to elucidate the… (More)
DOI: 10.1007/978-1-60761-700-6_12