Imaging of protein synthesis with puromycin.

@article{Goodman2012ImagingOP,
  title={Imaging of protein synthesis with puromycin.},
  author={Craig A Goodman and Philippe Douglas St Pierre and Troy A Hornberger},
  journal={Proceedings of the National Academy of Sciences of the United States of America},
  year={2012},
  volume={109 17},
  pages={
          E989; author reply E990
        }
}
With great interest, we read the work by Liu et al. (1), which described the development of an alkyne analog of puromycin for labeling and imaging of newly synthesized peptides. Available techniques for this type of measurement are very limited, and the work by Liu et al. (1) claimed that an alternative method, which is based on antipuromycin immunohistochemistry (SUnSET) (2), results in a subcellular localization of nascent peptides that is not consistent with the expected location of newly… CONTINUE READING

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Imaging protein synthesis in cells and tissues with an alkyne analog of puromycin.

  • Proceedings of the National Academy of Sciences of the United States of America
  • 2012

Novel insights into the regulation of skeletal muscle protein synthesis as revealed by a new nonradioactive in vivo technique

CA Goodman
  • FASEB J
  • 2011

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