Imaging of platelet-derived growth factor receptor β expression in glioblastoma xenografts using affibody molecule 111In-DOTA-Z09591.

@article{Tolmachev2014ImagingOP,
  title={Imaging of platelet-derived growth factor receptor β expression in glioblastoma xenografts using affibody molecule 111In-DOTA-Z09591.},
  author={Vladimir Tolmachev and Zohreh Varasteh and Hadis Honarvar and Seyed Jalal Hosseinimehr and Olof Eriksson and Per Jonasson and Fredrik Y. Frejd and Lars Bertil Abrahms{\'e}n and Anna Orlova},
  journal={Journal of nuclear medicine : official publication, Society of Nuclear Medicine},
  year={2014},
  volume={55 2},
  pages={294-300}
}
UNLABELLED The overexpression and excessive signaling of platelet-derived growth factor receptor β (PDGFRβ) has been detected in cancers, atherosclerosis, and a variety of fibrotic diseases. Radionuclide in vivo visualization of PDGFRβ expression might help to select PDGFRβ targeting treatment for these diseases. The goal of this study was to evaluate the feasibility of in vivo radionuclide imaging of PDGFRβ expression using an Affibody molecule, a small nonimmunoglobulin affinity protein… CONTINUE READING
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First clinical observations of HER2 specific [111In]ABY-025 metastatic detection capability in females with metastatic breast cancer [abstract

  • D Sandberg, A Wennborg, F Feldwisch
  • J Nucl Med
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