Imaging of organelles by electron microscopy reveals protein-protein interactions in mitochondria and chloroplasts.

@article{Dudkina2010ImagingOO,
  title={Imaging of organelles by electron microscopy reveals protein-protein interactions in mitochondria and chloroplasts.},
  author={Natalya V. Dudkina and Roman Kouřil and Jelle Bernard Bultema and Egbert J. Boekema},
  journal={FEBS letters},
  year={2010},
  volume={584 12},
  pages={
          2510-5
        }
}
Ongoing progress in electron microscopy (EM) offers now an opening to visualize cells at the nanoscale by cryo-electron tomography (ET). Large protein complexes can be resolved at near-atomic resolution by single particle averaging. Some examples from mitochondria and chloroplasts illustrate the possibilities with an emphasis on the membrane organization. Cryo-ET performed on non-chemically fixed, unstained, ice-embedded material can visualize specific large membrane protein complexes. In… CONTINUE READING

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Imaging of organelles by electron microscopy reveals protein - protein interactions in mitochondria and chloroplasts

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