Imaging of onset and progression of Alzheimer's disease with voxel-compression mapping of serial magnetic resonance images.

Abstract

BACKGROUND Early diagnosis and monitoring of the progression of Alzheimer's disease is important for the development of therapeutic strategies. To detect the earliest structural brain changes, individuals need to be studied before symptom onset. We used an imaging technique known as voxel-compression mapping to localise progressive atrophy in patients with… (More)

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