Imaging of experimental osteoarthritis in small animal models.

  title={Imaging of experimental osteoarthritis in small animal models.},
  author={Tom M Piscaer and Gerjo J. V. M. van Osch and J. A. N. Verhaar and Harrie Weinans},
  volume={45 3-4},
Normally, tissue alterations in small animal models for osteoarthritis (OA) are assessed by time-consuming and destructive histology or biochemical assays. Some high resolution imaging modalities are used for longitudinal monitoring of the OA disease process in vivo. microCT is one of these imaging modalities, which is known for superb high-resolution imaging of bone architecture alterations. A major drawback of microCT is that it has low soft-tissue contrast, which makes direct imaging of… CONTINUE READING


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