Imaging of cardiovascular structures using near-infrared femtosecond multiphoton laser scanning microscopy.

@article{SchenkeLayland2005ImagingOC,
  title={Imaging of cardiovascular structures using near-infrared femtosecond multiphoton laser scanning microscopy.},
  author={Katja Schenke-Layland and Iris Riemann and U A Stock and Karsten Koenig},
  journal={Journal of biomedical optics},
  year={2005},
  volume={10 2},
  pages={024017}
}
Multiphoton imaging represents a novel and very promising medical diagnostic technology for the high-resolution analysis of living biological tissues. We performed multiphoton imaging to analyzed structural features of extracellular matrix (ECM) components, e.g., collagen and elastin, of vital pulmonary and aortic heart valves. High-resolution autofluorescence images of collagenous and elastic fibers were demonstrated using multifluorophore, multiphoton excitation at two different wavelengths… CONTINUE READING