Imaging of basal cell carcinoma by high‐definition optical coherence tomography: histomorphological correlation. A pilot study

@article{Boone2012ImagingOB,
  title={Imaging of basal cell carcinoma by high‐definition optical coherence tomography: histomorphological correlation. A pilot study},
  author={Marc Boone and S Norrenberg and Gregor Borut Ernst Jemec and V{\'e}ronique del Marmol},
  journal={British Journal of Dermatology},
  year={2012},
  volume={167}
}
Summary Background  With the continued development of noninvasive therapies for basal cell carcinoma (BCC) such as photodynamic therapy and immune therapies, noninvasive diagnosis and monitoring become increasingly relevant. High‐definition optical coherence tomography (HD‐OCT) is a high‐resolution imaging tool, with micrometre resolution in both transversal and axial directions, enabling visualization of individual cells up to a depth of around 570 μm, and filling the imaging gap between… 
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108 Citations
Highly Influential Citations
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Background Citations
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108 Citations

Line‐field confocal optical coherence tomography of basal cell carcinoma: a descriptive study
TLDR
Line‐field confocal optical coherence tomography (LC‐OCT) is a new technology able to combine the technical advantages of reflectance confocal microscopy and OCT.
High‐definition optical coherence tomography algorithm for discrimination of basal cell carcinoma from clinical BCC imitators and differentiation between common subtypes
Preliminary studies have described morphological features of basal cell carcinoma (BCC) imaged by high‐definition optical coherence tomography (HD‐OCT) and suggested that this technique may aid in…
Imaging actinic keratosis by high‐definition optical coherence tomography. Histomorphologic correlation: a pilot study
TLDR
The study implies that high‐definition optical coherence tomography facilitates in vivo diagnosis of actinic keratosis and allows the grading of different actinic Keratosis lesions for increased clinical utility.
High‐definition optical coherence tomography algorithm for the discrimination of actinic keratosis from normal skin and from squamous cell carcinoma
Preliminary studies described morphological features of actinic keratosis (AK) and squamous cell carcinoma (SCC) imaged by High‐Definition Optical Coherence Tomography (HD‐OCT) and suggested that…
The utility of optical coherence tomography for diagnosis of basal cell carcinoma: a quantitative review
Optical coherence tomography (OCT) is a noninvasive near‐infrared light imaging technology that can be utilized to diagnose basal cell carcinomas (BCCs) based on specific morphological features.
Optical coherence tomography of basal cell carcinoma: influence of location, subtype, observer variability and image quality on diagnostic performance
TLDR
Much additional useful information was gathered that warranted further analysis in this trial, and is presented here.
Assessment of a scoring system for Basal Cell Carcinoma with multi‐beam optical coherence tomography
Multi‐beam optical coherence tomography (OCT) is a novel method of non‐invasive skin imaging allowing the evaluation of tissue at high level of lateral and axial resolution. It permits the horizontal…
Accuracy of optical coherence tomography for the diagnosis of superficial basal cell carcinoma: a prospective, consecutive, cohort study of 168 cases
TLDR
Potentially noninvasive imaging techniques, such as optical coherence tomography (OCT), may be useful to diagnose and manage patients with sBCC and obviate the need for biopsy.
Optical coherence tomography of actinic keratoses and basal cell carcinomas – differentiation by quantification of signal intensity and layer thickness
TLDR
There is a lack of systematic studies that give standardized information on signal intensity and layer thickness of AKs and BCCs, so there is a need for more studies to be conducted on this topic.
Histopathological correlates of basal cell carcinoma in the slice and en face imaging modes of high‐definition optical coherence tomography
TLDR
High‐definition optical coherence tomography (HD‐OCT) scanners have recently been developed, providing significantly higher resolution than conventional OCT, and are being developed for clinical use.
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