Imaging of osteoarthritis (OA) in the elderly is gaining importance because of the aging population. It requires knowledge about findings relevant for patient management and others which are abnormal findings, but part of normal aging without relevance for patient management due to lack of clinical symptoms. This review will provide information on what imaging techniques are best used for knee OA and how to systematically assess knee joint structures in order to cover the most common asymptomatic and symptomatic MR findings in OA. We will discuss which findings are typically found in older patients and which are likely to progress to severe pain and disability, finally leading to total joint replacement. The review may aid radiologists and referring clinicians to better understand the evolution of symptomatic OA and the current or future clinical significance of the most common symptomatic and asymptomatic findings.