Imaging of Functional Connectivity in the Mouse Brain

  title={Imaging of Functional Connectivity in the Mouse Brain},
  author={Brian R. White and Adam Q. Bauer and Abraham Z. Snyder and Bradley L. Schlaggar and Jin-Moo Lee and Joseph P. Culver},
  booktitle={PloS one},
Functional neuroimaging (e.g., with fMRI) has been difficult to perform in mice, making it challenging to translate between human fMRI studies and molecular and genetic mechanisms. A method to easily perform large-scale functional neuroimaging in mice would enable the discovery of functional correlates of genetic manipulations and bridge with mouse models of disease. To satisfy this need, we combined resting-state functional connectivity mapping with optical intrinsic signal imaging (fcOIS). We… CONTINUE READING
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