Imaging mass spectrometry of gastric carcinoma in formalin-fixed paraffin-embedded tissue microarray.

@article{Morita2010ImagingMS,
  title={Imaging mass spectrometry of gastric carcinoma in formalin-fixed paraffin-embedded tissue microarray.},
  author={Yoshifumi Morita and Koji Ikegami and Naoko Goto-Inoue and Takahiro Hayasaka and Nobuhiro Zaima and Hiroki Tanaka and Takashi Uehara and Tomohiko Setoguchi and Takanori Sakaguchi and Hisashi Igarashi and Haruhiko Sugimura and Mitsutoshi Setou and Hiroyuki Konno},
  journal={Cancer science},
  year={2010},
  volume={101 1},
  pages={267-73}
}
The popularity of imaging mass spectrometry (IMS) of tissue samples, which enables the direct scanning of tissue sections within a short time-period, has been considerably increasing in cancer proteomics. Most pathological specimens stored in medical institutes are formalin-fixed; thus, they had been regarded to be unsuitable for proteomic analyses, including IMS, until recently. Here, we report an easy-to-use screening method that enables the analysis of multiple samples in one experiment… CONTINUE READING