Imaging lymphoid tissues in nonhuman primates to understand SIV pathogenesis and persistence.

@article{Deleage2016ImagingLT,
  title={Imaging lymphoid tissues in nonhuman primates to understand SIV pathogenesis and persistence.},
  author={Claire Deleage and Baris Turkbey and Jacob D Estes},
  journal={Current opinion in virology},
  year={2016},
  volume={19},
  pages={
          77-84
        }
}
CD4+ T cells are the primary HIV-1 target cell, with the vast majority of these cells residing within lymphoid tissue compartments throughout the body. Predictably, HIV-1 infection, replication, localization, reservoir establishment and persistence, as well as associated host immune and inflammatory responses and disease pathology principally take place within the tissues of the immune system. By virture of the fact that the virus-host struggle is played out within lymphoid and additional… CONTINUE READING
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Current Opinion in Virology 2016

C Deleage, WS Wietgrefe, +12 authors JD Estes
  • Pathog Immun
  • 2016