Imaging live-cell dynamics and structure at the single-molecule level.

@article{Liu2015ImagingLD,
  title={Imaging live-cell dynamics and structure at the single-molecule level.},
  author={Zhe Liu and Luke D Lavis and Eric Betzig},
  journal={Molecular cell},
  year={2015},
  volume={58 4},
  pages={
          644-59
        }
}
Observation of molecular processes inside living cells is fundamental to a quantitative understanding of how biological systems function. Specifically, decoding the complex behavior of single molecules enables us to measure kinetics, transport, and self-assembly at this fundamental level that is often veiled in ensemble experiments. In the past decade, rapid developments in fluorescence microscopy, fluorescence correlation spectroscopy, and fluorescent labeling techniques have enabled new… CONTINUE READING

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