Imaging human mesolimbic dopamine transmission with positron emission tomography: I. Accuracy and precision of D(2) receptor parameter measurements in ventral striatum.

@article{Mawlawi2001ImagingHM,
  title={Imaging human mesolimbic dopamine transmission with positron emission tomography: I. Accuracy and precision of D(2) receptor parameter measurements in ventral striatum.},
  author={Osama Mawlawi and Diana Carolina Salamanca Martinez and Mark Slifstein and Allegra I. Broft and R. N. Chatterjee and Dah-Ren Hwang and Yiyun Huang and Norman Simpson and Kim Ngo and Ronald L van Heertum and Marc Laruelle},
  journal={Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism},
  year={2001},
  volume={21 9},
  pages={1034-57}
}
Dopamine transmission in the ventral striatum (VST), a structure which includes the nucleus accumbens, ventral caudate, and ventral putamen, plays a critical role in the pathophysiology of psychotic states and in the reinforcing effects of virtually all drugs of abuse. The aim of this study was to assess the accuracy and precision of measurements of D(2) receptor availability in the VST obtained with positron emission tomography on the high-resolution ECAT EXACT HR+ scanner (Siemens Medical… CONTINUE READING
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