Imaging hemodynamics

  title={Imaging hemodynamics},
  author={D. K. Jennings and Natarajan Raghunand and Robert J. Gillies},
  journal={Cancer and Metastasis Reviews},
Microvascular permeability is a pharmacologic indicator of tumor response to therapy, and it is expected that this biomarker will evolve into a clinical surrogate endpoint and be integrated into protocols for determining patient response to antiangiogenic or antivascular therapies. This review discusses the physiological context of vessel permeability in an imaging setting, how it is affected by active and passive transport mechanisms, and how it is described mathematically for both theoretical… CONTINUE READING