Imaging growth and isocitrate dehydrogenase 1 mutation are independent predictors for diffuse low-grade gliomas.

@article{Goz2014ImagingGA,
  title={Imaging growth and isocitrate dehydrogenase 1 mutation are independent predictors for diffuse low-grade gliomas.},
  author={Catherine Goz{\'e} and Marie Blonski and Guillaume Le Maistre and Luc Bauchet and Edouard Dezamis and Philippe Page and Pascale Varlet and Laurent Capelle and Bertrand Devaux and Luc Taillandier and Hugues Duffau and Johan Pallud},
  journal={Neuro-oncology},
  year={2014},
  volume={16 8},
  pages={1100-9}
}
BACKGROUND We explored whether spontaneous imaging tumor growth (estimated by the velocity of diametric expansion) and isocitrate dehydrogenase 1 (IDH1) mutation (estimated by IDH1 immunoexpression) were independent predictors of long-term outcomes of diffuse low-grade gliomas in adults. METHODS One hundred thirty-one adult patients with newly diagnosed supratentorial diffuse low-grade gliomas were retrospectively studied. RESULTS Isocitrate dehydrogenase 1 mutations were present in 107… CONTINUE READING
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Diffuse Low-Grade Gliomas in Adults

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Springer International Publishing • 2017
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