Imaging delta- and mu-opioid receptors by PET in lung carcinoma patients.

  title={Imaging delta- and mu-opioid receptors by PET in lung carcinoma patients.},
  author={Igal Madar and Badreddine Bencherif and John Lever and Richard F. Heitmiller and Stephen Chi-Tin Yang and Malcolm Brock and Julie Brahmer and Hayden T. Ravert and Robert F. Dannals and James Frost},
  journal={Journal of nuclear medicine : official publication, Society of Nuclear Medicine},
  volume={48 2},
UNLABELLED In the present study, we measured the kinetics and distribution in vivo of the selective delta-opioid antagonist 11C-methylnaltrindole (11C-MeNTI) and the mu-opioid agonist 11C-carfentanil (11C-CFN) in patients with lung carcinoma using PET. METHODS Paired measurements of 11C-MeNTI and 11C-CFN binding were performed in biopsy-proven small-cell (n = 2), squamous (n = 2), and adenocarcinoma (n = 3) lung cancer patients. Dynamic PET scans of increasing duration (0.5-8 min) were… CONTINUE READING


Publications citing this paper.
Showing 1-10 of 15 extracted citations

Similar Papers

Loading similar papers…