Imaging corticospinal degeneration in neonatal rats with unilateral cerebral infarction.

@article{Lama2011ImagingCD,
  title={Imaging corticospinal degeneration in neonatal rats with unilateral cerebral infarction.},
  author={Sanju Lama and Min Qiao and A Kirton and Sunny Sun and Elise L Cheng and Tadeusz Foniok and Ursula I. Tuor},
  journal={Experimental neurology},
  year={2011},
  volume={228 2},
  pages={192-9}
}
Recent human studies indicate that magnetic resonance (MR) imaging, particularly diffusion weighted imaging, detects abnormalities within the descending cortico-spinal tract following stroke. Whether these changes are directly related to processes of axonal degeneration and how MR changes (e.g. apparent diffusion coefficient of water (ADC) and T(2)) vary in their diagnostic utility over time is not known. The present study demonstrates that a commonly used rat model of neonatal transient… CONTINUE READING