Imaging characteristics of DHOG, a hepatobiliary contrast agent for preclinical microCT in mice.

@article{Henning2008ImagingCO,
  title={Imaging characteristics of DHOG, a hepatobiliary contrast agent for preclinical microCT in mice.},
  author={Tobias D. Henning and Axel W. Weber and Jan S. Bauer and Reinhard Meier and Janette Carlsen and Elizabeth J Sutton and Sven Prevrhal and Sibylle Ilse Ziegler and Hubertus Feu\ssner and Heike E. Daldrup-Link and Ernst J. Rummeny},
  journal={Academic radiology},
  year={2008},
  volume={15 3},
  pages={342-9}
}
RATIONALE AND OBJECTIVES This study was performed to assess the imaging characteristics and pharmacokinetics of 1,3-Bis-[7-(3-amino-2,4,6-triiodophenyl)-heptanoyl]-2-oleoyl glycerol (DHOG, Fenestra LC), a hepatobiliary contrast agent for microCT. MATERIALS AND METHODS We investigated the abdomen of 18 female C3H mice in a MicroCAT II microCT scanner before contrast agent injection and at multiple time points up to 48 hours after intravenous injection of DHOG (1 g I/kg body weight). The… CONTINUE READING