Imaging brain oxygenation with MRI using blood oxygenation approaches: methods, validation, and clinical applications.

@article{Christen2013ImagingBO,
  title={Imaging brain oxygenation with MRI using blood oxygenation approaches: methods, validation, and clinical applications.},
  author={Thomas Christen and Divya Sanam Bolar and G Zaharchuk},
  journal={AJNR. American journal of neuroradiology},
  year={2013},
  volume={34 6},
  pages={1113-23}
}
SUMMARY In many pathophysiologic situations, including brain neoplasms, neurodegenerative disease, and chronic and acute ischemia, an imbalance exists between oxygen tissue consumption and delivery. Furthermore, oxygenation changes following a stress challenge, such as with carbogen gas or acetazolamide, can yield information about cerebrovascular reactivity. The unique sensitivity of the BOLD effect to the presence of deoxyhemoglobin has led to its widespread use in the field of cognitive… CONTINUE READING
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