Imaging brain amyloid deposition using grating-based differential phase contrast tomography

  title={Imaging brain amyloid deposition using grating-based differential phase contrast tomography},
  author={B. R. Pinzer and M. Cacquevel and Peter Modregger and S. A. McDonald and J. C. Bensadoun and T. Thuering and P. Aebischer and Marco Stampanoni},
One of the core pathological features of Alzheimer's disease (AD) is the accumulation of amyloid plaques in the brain. Current efforts of medical imaging research aim at visualizing amyloid plaques in living patients in order to evaluate the progression of the pathology, but also to facilitate the diagnosis of AD at the prodromal stage. In this study, we evaluated the capabilities of a new experimental imaging setup to image amyloid plaques in the brain of a transgenic mouse model of Alzheimer… CONTINUE READING
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TOMCAT: a beamline for tomographic microscopy and coherent radiology experiments

  • M. Stampanoni, A. Groso, +7 authors R. Abela
  • Synchrotron Radiat. Instrum. Pts
  • 2007
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