Imaging brain activation: simple pictures of complex biology.

  title={Imaging brain activation: simple pictures of complex biology.},
  author={Gerald A. Dienel and Nancy F. Cruz},
  journal={Annals of the New York Academy of Sciences},
Elucidation of biochemical, physiological, and cellular contributions to metabolic images of brain is important for interpretation of images of brain activation and disease. Discordant brain images obtained with [(14)C]deoxyglucose and [1- or 6-(14)C]glucose were previously ascribed to increased glycolysis and rapid [(14)C]lactate release from tissue, but direct proof of [(14)C]lactate release from activated brain structures is lacking. Analysis of factors contributing to images of focal… CONTINUE READING
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