Imaging biomarkers associated with cognitive decline: a review.

@article{McConathy2015ImagingBA,
  title={Imaging biomarkers associated with cognitive decline: a review.},
  author={Jonathan E McConathy and Yvette I. Sheline},
  journal={Biological psychiatry},
  year={2015},
  volume={77 8},
  pages={685-92}
}
In evaluating disease changes, it is critical to have measurements that are sensitive, specific, and reliable. Cognitive decline, particularly in the context of Alzheimer's disease, is an area that has attracted numerous recent studies, and the proposed biomarkers used in these investigations need to be validated. In this review, we highlight studies with important implications about the role of imaging biomarkers in cognitive decline and dementia as well as in distinguishing preclinical… CONTINUE READING

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