Imaging and Methotrexate Response Monitoring of Systemic Inflammation in Arthritic Rats Employing the Macrophage PET Tracer [18F]Fluoro-PEG-Folate

@inproceedings{Chandrupatla2018ImagingAM,
  title={Imaging and Methotrexate Response Monitoring of Systemic Inflammation in Arthritic Rats Employing the Macrophage PET Tracer [18F]Fluoro-PEG-Folate},
  author={Durga M S H Chandrupatla and Gerrit Jansen and Elise Mantel and Philip S Low and Takami Matsuyama and Ren{\'e} J. P. Musters and Albert D. Windhorst and Adriaan A. Lammertsma and Carla F. M. Molthoff and Conny J van der Laken},
  booktitle={Contrast media & molecular imaging},
  year={2018}
}
Background In rheumatoid arthritis, articular inflammation is a hallmark of disease, while the involvement of extra-articular tissues is less well defined. Here, we examined the feasibility of PET imaging with the macrophage tracer [18F]fluoro-PEG-folate, targeting folate receptor β (FRβ), to monitor systemic inflammatory disease in liver and spleen of… CONTINUE READING