Imaging Transcriptional Regulation of Eukaryotic mRNA Genes: Advances and Outlook.

  title={Imaging Transcriptional Regulation of Eukaryotic mRNA Genes: Advances and Outlook.},
  author={Jie Yao},
  journal={Journal of molecular biology},
  volume={429 1},
  • Jie Yao
  • Published 2017
  • Biology, Medicine
  • Journal of molecular biology
Regulation of eukaryotic transcription in vivo occurs at distinct stages. Previous research has identified many active or repressive transcription factors (TFs) and core transcription components and studied their functions in vitro and in vivo. Nonetheless, how individual TFs act in concert to regulate mRNA gene expression in a single cell remains poorly understood. Direct observation of TF assembly and disassembly and various biochemical reactions during transcription of a single-copy gene in… Expand
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