Imaging Switchable Protein Interactions with an Active Porous Polymer Support.
@article{Dutta2020ImagingSP, title={Imaging Switchable Protein Interactions with an Active Porous Polymer Support.}, author={Chayan Dutta and Logan D. C. Bishop and Jorge Zepeda O and Sudeshna Chatterjee and Charlotte Flatebo and Christy F. Landes}, journal={The journal of physical chemistry. B}, year={2020} }
Mechanistic details about how local physicochemistry of porous interfaces drives protein transport mechanisms are necessary to optimize biomaterial applications. Cross-linked hydrogels made of stimuli-responsive polymers have potential for active protein capture and release through tunable steric and chemical transformations. Simultaneous monitoring of dynamic changes in both protein transport and interfacial polymer structure is an experimental challenge. We use single-particle tracking (SPT…
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