Imaging Plasmodium immunobiology in the liver, brain, and lung.

  title={Imaging Plasmodium immunobiology in the liver, brain, and lung.},
  author={Ute Frevert and Ad{\'e}la Nacer and Mynthia Cabrera and Alexandru Movila and Maike Leberl},
  journal={Parasitology international},
  volume={63 1},
Plasmodium falciparum malaria is responsible for the deaths of over half a million African children annually. Until a decade ago, dynamic analysis of the malaria parasite was limited to in vitro systems with the typical limitations associated with 2D monocultures or entirely artificial surfaces. Due to extremely low parasite densities, the liver was considered a black box in terms of Plasmodium sporozoite invasion, liver stage development, and merozoite release into the blood. Further, nothing… CONTINUE READING
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