Imaging Genomics of Glioblastoma: Biology, Biomarkers, and Breakthroughs.

  title={Imaging Genomics of Glioblastoma: Biology, Biomarkers, and Breakthroughs.},
  author={Safwan Moton and Mohamed G Elbanan and Pascal O. Zinn and Rivka R. Colen},
  journal={Topics in magnetic resonance imaging : TMRI},
  volume={24 3},
Glioblastoma is regarded as the most aggressive and most common primary malignant brain tumor in adults. Despite advancements in chemotherapy and radiotherapy, prognosis and overall survival of glioblastoma patients remain dismal. Recently, progresses in genetic profiling have increased our understanding of the underlying heterogenous molecular nature of this aggressive tumor. Several prognostic and predictive molecular biomarkers have been identified that have been linked to patient's survival… CONTINUE READING
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