Imaging , Diagnosis , Prognosis A 20 , ABIN-1 / 2 , and CARD 11 Mutations and Their Prognostic Value in Gastrointestinal Diffuse Large B-Cell Lymphoma

@inproceedings{Dong2011ImagingD,
  title={Imaging , Diagnosis , Prognosis A 20 , ABIN-1 / 2 , and CARD 11 Mutations and Their Prognostic Value in Gastrointestinal Diffuse Large B-Cell Lymphoma},
  author={Gehong Dong and Estelle Chanudet and Naiyan Zeng and Alex Appert and Yun-Wen Chen and Wing-yan Au and Rifat A. Hamoudi and Adam J Watkins and Hongtao Ye and Hongxiang Liu and Zifen Gao and Shih-sung Chuang and Gopesh Srivastava and Ming-Qing Du},
  year={2011}
}
Purpose: Diffuse large B-cell lymphoma (DLBCL) is a heterogeneous group of aggressive lymphomas with the activated B-cell–like subtype characterized by constitutive NF-kB activation. Activating mutations of CARD11 and inactivating mutations of A20 are frequent events in DLBCL. However, the full extent of genetic alterations in the NF-kB pathway regulators and their potential prognostic value in DLBCL remain to be investigated. We investigated the genetic abnormalities of CARD11, A20, and ABIN-1… CONTINUE READING
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