Image reconstruction reveals the complex molecular organization of adenovirus.

@article{Stewart1991ImageRR,
  title={Image reconstruction reveals the complex molecular organization of adenovirus.},
  author={Phoebe L. Stewart and Roger M. Burnett and M Cyrklaff and Stephen D. Fuller},
  journal={Cell},
  year={1991},
  volume={67 1},
  pages={145-54}
}
The three-dimensional structure of adenovirus has been determined by image reconstruction from cryo-electron micrographs. Comparison with the high resolution X-ray crystal structure of hexon, the major capsid protein, enabled an unusually detailed interpretation of the density map and confirmed the validity of the reconstruction. The hexon packing in the capsid shows more extensive intermolecular interfaces between facets than previously proposed. The reconstruction provides the first three… CONTINUE READING

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