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  title={Image More to Save More},
  author={Aaron P. Tansy and Jason D. Hinman and Kwan L. Ng and Mateo Calderon-Arnulphi and Royya Modir and Fiona Chatfield and David S. Liebeskind},
  journal={Frontiers in Neurology},
Recent successful endovascular stroke trials have provided unequivocal support for these therapies in selected patients with large-vessel occlusive acute ischemic stroke. In this piece, we briefly review these trials and their utilization of advanced neuroimaging techniques that played a pivotal role in their success through targeted patient selection. In this context, the unique challenges and opportunity for advancement in current stroke networks’ routine delivery of care created by these… 
Fluid-Attenuated Inversion Recovery Vascular Hyperintensity Topography, Novel Imaging Marker for Revascularization in Middle Cerebral Artery Occlusion
Higher FVH-ASPECTS measured outside the DWI lesion is associated with good clinical outcomes in patients undergoing endovascular treatment and can serve as an imaging selection marker for ET in acute middle cerebral artery occlusion.
Resting state functional magnetic resonance imaging processing techniques in stroke studies
The brain connectivity and resting state networks are described with a focus on rsf MRI imaging in stroke studies, and techniques for preprocessing of the rsfMRI for stroke patients are reviewed, followed by brain connectivity processing techniques.


Collaterals in endovascular therapy for stroke.
The collateral circulation is defined, methods of its measurement are reviewed, and recent clinical data on its impact in endovascular therapy for acute ischemic stroke are presented.
Use of Perfusion Imaging and Other Imaging Techniques to Assess Risks/Benefits of Acute Stroke Interventions
A framework and potential algorithm-based methodology for imaging modality selection and utilization for stroke clinical care, with a focus on the imaging modalities that best identify critical inclusion and exclusion criteria is proposed.
Endovascular therapy for ischemic stroke with perfusion-imaging selection.
In patients with ischemic stroke with a proximal cerebral arterial occlusion and salvageable tissue on CT perfusion imaging, early thrombectomy with the Solitaire FR stent retriever, as compared with alteplase alone, improved reperfusion, early neurologic recovery, and functional outcome.
A trial of imaging selection and endovascular treatment for ischemic stroke.
A favorable penumbral pattern on neuroimaging did not identify patients who would differentially benefit from endovascular therapy for acute ischemic stroke, nor was embolectomy shown to be superior to standard care.
The Goldilocks Dilemma in Acute Ischemic Stroke
This perspective piece proposes that key clinical criteria highlighted in past trials must be applied in service of a model that accounts for the nuanced, dynamic nature of acute ischemic stroke better than the prevailing “time is brain” model.
Randomized assessment of rapid endovascular treatment of ischemic stroke.
BACKGROUND Among patients with a proximal vessel occlusion in the anterior circulation, 60 to 80% of patients die within 90 days after stroke onset or do not regain functional independence despite
Collateral Flow Predicts Response to Endovascular Therapy for Acute Ischemic Stroke
The data indicate that angiographic collateral grade determines the recanalization rate after endovascular revascularization therapy, and may help guide treatment decision-making in acute cerebral ischemia.
National Institutes of Health Stroke Scale Score Is Poorly Predictive of Proximal Occlusion in Acute Cerebral Ischemia
High NIHSS score correlates with the presence of a proximal arterial occlusion in patients presenting with acute cerebral ischemia, and the finding of minimal clinical deficits should not deter urgent angiographic imaging in otherwise appropriate patients suspected of acute stroke.
A randomized trial of intraarterial treatment for acute ischemic stroke.
In patients with acute ischemic stroke caused by a proximal intracranial occlusion of the anterior circulation, intraarterial treatment administered within 6 hours after stroke onset was effective and safe.