Image Analysis Quantification of Sticking and Picking Events of Pharmaceutical Powders Compressed on a Rotary Tablet Press Simulator

@article{Mollereau2013ImageAQ,
  title={Image Analysis Quantification of Sticking and Picking Events of Pharmaceutical Powders Compressed on a Rotary Tablet Press Simulator},
  author={Germinal Mollereau and Vincent Mazel and Virginie Busignies and Pierre Tchoreloff and Fabrice Mouveaux and Philippe Rivi{\`e}re},
  journal={Pharmaceutical Research},
  year={2013},
  volume={30},
  pages={2303-2314}
}
The aim of this work was to develop a quantification method based on image analysis, able to characterize sticking during pharmaceutical tableting. Relationship between image analysis features and relevant mechanical parameters recorded on an instrumented tablet press simulator were investigated. Image analysis, based on gray levels co-occurrence matrices (GLCM), generated textural features of the tablet surface. The tableting simulator (Stylcam® 200R, Medelpharm), instrumented with force and… CONTINUE READING