Iloprost enhances survival of axial-pattern skin flaps in an ischemia-reperfusion model.

@article{Rajagopal1995IloprostES,
  title={Iloprost enhances survival of axial-pattern skin flaps in an ischemia-reperfusion model.},
  author={U Rajagopal and Rebecca M Friedman and Jack B. Robinson and Rod J. Rohrich},
  journal={Plastic and reconstructive surgery},
  year={1995},
  volume={95 5},
  pages={884-7}
}
Iloprost, a stable prostacyclin analogue, significantly enhances the survival of an axial-pattern groin flap in rats after ischemia-reperfusion. Treated flaps showed viability over 90 percent of their area 7 days after an 8-hour ischemic episode, whereas the saline-treated controls were viable over only 20 percent of their area (p = 0.002). This effect was… CONTINUE READING