Iloprost Affects Macrophage Activation and CCL2 Concentrations in a Microdialysis Model in Rats

Abstract

The hypothesis that locally-released iloprost, a synthetic prostacyclin analog, affects macrophage phenotype at a microdialysis implant in the subcutaneous space of rats was tested. Macrophage activation towards alternatively-activated phenotypes using pharmaceutical release is of interest to improve integration of implants and direct the foreign body… (More)
DOI: 10.1007/s11095-017-2277-1

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