Iloprost, a prostacyclin (PGI2) analogue, reduces liver injury in hepatic ischemia-reperfusion in rats.

@article{Gedik2009IloprostAP,
  title={Iloprost, a prostacyclin (PGI2) analogue, reduces liver injury in hepatic ischemia-reperfusion in rats.},
  author={Ercan Gedik and S. Z. Siretioglu Girgin and Basra Deniz Obay and Hayrettin Ozturk and H. Serdar Ozturk and Huseyin Buyukbayram},
  journal={Acta cirurgica brasileira},
  year={2009},
  volume={24 3},
  pages={
          226-32
        }
}
PURPOSE To evaluate the effects of iloprost a prostacyclin analogue on the hepatic IR injury in rats. METHODS Forty male Sprague-Dawley rats (250-300 g) were divided into four groups each containing 10 rats;(1)--controls: data from unmanipulated animals; (2) sham group: rats subjected to the surgical procedure, except for liver I/R, and given saline; (3) I/R group: rats that underwent liver ischemia for 45 min followed by reperfusion for 45 min; (4) IR/ Iloprost group: rats pretreated with… CONTINUE READING

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