Iloneoside: a cytotoxic ditigloylated pregnane glycoside from the leaves of Gongronema latifolium Benth.

@article{Gyebi2018IloneosideAC,
  title={Iloneoside: a cytotoxic ditigloylated pregnane glycoside from the leaves of Gongronema latifolium Benth.},
  author={Gideon Ampoma Gyebi and Joseph Oluwatope Adebayo and Olufunke E. Olorundare and Antoni Pardede and Masayuki Ninomiya and Afolabi Olanrewaju Saheed and Abiola S Babatunde and Mamoru Koketsu},
  journal={Natural product research},
  year={2018},
  volume={32 24},
  pages={
          2882-2886
        }
}
Gongronema latifolium Benth (Asclepiadaceae) is an edible-green-leafy vegetable with known medicinal value. A chemical investigation of the 80% methanolic extract of the leaves led to the isolation of a new pregnane glycoside: iloneoside (3-O-[6-deoxy-3-O-methyl-β-D-allopyranosyl-(1→14)-β-D-oleandropyranosyl]-11,12-di-O-tigloyl-17β-marsdenin), together with four known constituents. Their chemical structures were determined by spectroscopic analysis. The isolates were tested for their in vitro… CONTINUE READING

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