Illuminating the metastatic process

  title={Illuminating the metastatic process},
  author={Erik Sahai},
  journal={Nature Reviews Cancer},
Until recently most studies of metastasis only measured the end point of the process — macroscopic metastases. Although these studies have provided much useful information, the details of the metastatic process remain somewhat mysterious owing to difficulties in studying cell behaviour with high spatial and temporal resolution in vivo. The use of luminescent and fluorescent proteins and developments in optical imaging technology have enabled the direct observation of cancer cells spreading from… CONTINUE READING
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