Ileal mucosal growth during intraluminal infusion of ethylamine or putrescine.

@article{Seidel1985IlealMG,
  title={Ileal mucosal growth during intraluminal infusion of ethylamine or putrescine.},
  author={Edward R. Seidel and Mari K. Haddox and Leonard R. Johnson},
  journal={The American journal of physiology},
  year={1985},
  volume={249 4 Pt 1},
  pages={G434-8}
}
Either ethylamine or the diamine putrescine was infused at the rate of 1 mumol/h for 66 h into the ileal lumen of rats. Total mucosal RNA, DNA, and protein content was greater in amine-treated rats than in rats receiving 0.9% NaCl. Growth was greatest in the mucosa surrounding the tip of the infusion catheter but was also observed 9 cm proximal and distal to the catheter tip. Infusion of these amines induced the activity of the enzymes ornithine and S-adenosylmethionine decarboxylase. Ornithine… CONTINUE READING