Ileal Mucosal and Fecal Pancreatitis Associated Protein Levels Reflect Severity of Salmonella Infection in Rats

@article{Ampting2008IlealMA,
  title={Ileal Mucosal and Fecal Pancreatitis Associated Protein Levels Reflect Severity of Salmonella Infection in Rats},
  author={Marleen T J Van Ampting and Wendy Rodenburg and Carolien Vink and Evelien Kramer and Arjan J. Schonewille and Jaap Keijer and Roelof van der Meer and Ingeborg M. J. Bovee-Oudenhoven},
  journal={Digestive Diseases and Sciences},
  year={2008},
  volume={54},
  pages={2588-2597}
}
Background Microbial infections induce ileal pancreatitis-associated protein/regenerating gene III (PAP/RegIII) mRNA expression. Despite increasing interest, little is known about the PAP/RegIII protein. Therefore, ileal mucosal PAP/RegIII protein expression, localization, and fecal excretion were studied in rats upon Salmonella infection. Results Salmonella infection increased ileal mucosal PAP/RegIII protein levels in enterocytes located at the crypt-villus junction. Increased colonization… CONTINUE READING
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