Ileal Involvement Is Age Dependent in Pediatric Crohn's Disease

@article{Meinzer2005IlealII,
  title={Ileal Involvement Is Age Dependent in Pediatric Crohn's Disease},
  author={Ulrich Meinzer and Maja Idestr{\"o}m and Corinne Alberti and Michel Peuchmaur and Nadia Belarbi and Marc Bella{\"i}che and Jean Francois Mougenot and Jean Pierre C{\'e}zard and Yigael Finkel and Jean-Pierre Hugot},
  journal={Inflammatory Bowel Diseases},
  year={2005},
  volume={11},
  pages={639–644}
}
Background: Lymphoid follicles (LFs) have been suggested to play a role at the early stage of Crohn's disease (CD) lesions. In the small bowel, LFs are grouped, forming Peyer's patches, which develop early in fetal life, grow in size and number until puberty, and undergo involution. In contrast, colonic LFs are isolated and undergo little change during life. As a result, if LFs play a role in the occurrence of CD lesions, the distribution of ileal and colonic lesions is expected to be altered… 
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...

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