Ikaros isoform x is selectively expressed in myeloid differentiation.

Abstract

The Ikaros gene is alternately spliced to generate multiple DNA-binding and nonbinding isoforms that have been implicated as regulators of hematopoiesis, particularly in the lymphoid lineages. Although early reports of Ikaros mutant mice focused on lymphoid defects, these mice also show significant myeloid, erythroid, and stem cell defects. However, the… (More)

Topics

6 Figures and Tables

Slides referencing similar topics