Ii. Development of Thymus-leukemia Antigen-positive and -negative Suppressor T Cells That Differ in Their Regulatory Function* Medical School. Animals Were Housed in Conventional Animal Rooms during Administration Of

Abstract

Studies of adult BALB/c mice given total lymphoid irradiation (TLI; 3,400 rad) 1 have shown that both heterologous proteins and allogeneic bone marrow (BM) cells injected into irradiated mice evoke a state of tolerance rather than immunity (1). The ease of induction of tolerance to protein antigens appears to be related to the development of a population of… (More)

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