IgM anti-GM1 antibodies in the Guillain-Barré syndrome: a serological predictor of the clinical course.

  title={IgM anti-GM1 antibodies in the Guillain-Barr{\'e} syndrome: a serological predictor of the clinical course.},
  author={Einar Bech and Torben Falck Orntoft and Leif Percival Andersen and Peter Skinh\oj and J. Jakobsen},
  journal={Journal of neuroimmunology},
  volume={72 1},
It has been suggested that antibodies against GM1 are involved in the pathogenesis of the Guillain-Barré syndrome (GBS). Recently, we have developed a standardized ELISA assay for anti-GM1 antibodies of IgM type well-suited for longitudinal patient studies. The relationship between serum antibodies against GM1 and Campylobacter jejuni was investigated in patients with GBS and in patients with C. jejuni infection. Patients with a short-lasting anti-GM1 elevation had a fast recovery, whereas… CONTINUE READING

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