Corpus ID: 7379334

IgM-Fc receptor-mediated phagocytosis of rat macrophages.

  title={IgM-Fc receptor-mediated phagocytosis of rat macrophages.},
  author={F. Uher and I. Dobronyi and J. Gergel},
  volume={42 3},
The features and function of IgM-FcR of rat peritoneal macrophages were studied. Macrophages specifically bind and phagocytose ox red blood cells coated with rat IgM (EA-IgM) through a specific receptor. This receptor is trypsin sensitive and its activity requires Ca++ ions. Both sodium azide and low temperature (4 degrees) inhibit the bindings as well as ingestion of EA-IgM by macrophages, suggesting the metabolically dependent character of the interaction between EA-IgM and macrophages… Expand
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