IgG4‐related disease with hypergammaglobulinemic hyperviscosity and retinopathy

  title={IgG4‐related disease with hypergammaglobulinemic hyperviscosity and retinopathy},
  author={P. Wong and A. Fung and A. Gerrie and G. Moloney and D. Maberley and D. Rossman and V. White and D. Collins and R. Coupland and Luke Y C Chen},
  journal={European Journal of Haematology},
  • P. Wong, A. Fung, +7 authors Luke Y C Chen
  • Published 2013
  • Medicine
  • European Journal of Haematology
  • Immunoglobulin G4‐related disease (IgG4‐RD) is a recently described entity with protean manifestations. We describe a novel case of IgG4‐RD with hypergammaglobulinemic hyperviscosity responsive to fludarabine and rituximab. A 33‐year‐old Asian man developed bilateral lacrimal gland and submandibular salivary gland swelling with cervical lymphadenopathy. Biopsies of the affected tissues revealed reactive follicular hyperplasia. Seven years later, he presented with bilateral retinal hemorrhages… CONTINUE READING
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