IgG subclass responses to pigeon intestinal mucin are related to development of pigeon fanciers' lung.


BACKGROUND Pigeon fanciers' lung (PFL) is a form of extrinsic allergic alveolitis. Affected individuals produce antibodies to various pigeon antigens, and the resulting immune complexes are thought to initiate the disease. However, high antibody titres also occur in some asymptomatic individuals. Previously attention has focused on protein antigens, but we… (More)


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