IgG-neutralized influenza virus undergoes primary, but not secondary uncoating in vivo.

@article{Rigg1989IgGneutralizedIV,
  title={IgG-neutralized influenza virus undergoes primary, but not secondary uncoating in vivo.},
  author={R J Rigg and Andrew S. Carver and Nigel J. Dimmock},
  journal={The Journal of general virology},
  year={1989},
  volume={70 ( Pt 8)},
  pages={2097-109}
}
Even when neutralized by saturating amounts of monoclonal IgG directed against the haemagglutinin, influenza virus attaches to cells with kinetics similar to those of infectious virus. It then enters those cells and is uncoated; its RNA becomes localized within the nucleus and its lipid envelope and associated proteins remain in the cytoplasm. In this report we show that despite the apparent normality of these early stages of virus-cell interaction, neutralized virus underwent no detectable… CONTINUE READING

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