IgG-loaded hyaluronan-based dissolving microneedles for intradermal protein delivery.

Abstract

Dissolving microneedles are an attractive approach for non-invasive delivery of drugs via the skin, particularly when the doses are in the microgram or low-milligram range. The aim of the study was to develop hyaluronan-based, monoclonal IgG-loaded microneedles for intradermal delivery enabling efficient penetration and rapid dissolution in the skin while… (More)
DOI: 10.1016/j.jconrel.2015.10.002

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