IgG-Fc receptors and the clinical relevance of their polymorphisms.

  title={IgG-Fc receptors and the clinical relevance of their polymorphisms.},
  author={Masja de Haas},
  journal={Wiener klinische Wochenschrift},
  volume={113 20-21},
Receptors for the Fc part of IgG form the bridge between immune complexes, antibodies and blood cells. Besides phagocytes, such as granulocytes and monocytes, also lymphocytes and platelets express members of the large family of IgG-Fc receptors or Fc gamma Rs. Three main classes of leukocyte Fc gamma Rs can be distinguished: Fc gamma RI, Fc gamma RII and Fc gamma RIII. Depending on the type of intracellular domain of the leukocyte Fc gamma Rs, interaction of a cell with an antibody-sensitized… CONTINUE READING
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